ARCHIVES
Year 2026 · Volume 6 · Issue 5
Original Article
Phytochemical Profiling and In-Vitro Anti-Inflammatory Activity of the Aqueous Ethanolic Extract of the Aerial Parts of Abutilon Indicum
A.Gowtham Sashtha1
S. Mohamed Halith2
R. Praveen3
R.Praveen Kumar4
S. Praveen Kumar5
A.B. Preethi6
K. Prema7
1 Assistant professor, Department of Pharmacology, Dhanalakshmi Srinivasan College of pharmacy, Perambalur, Tamil Nadu, India. 2 Principal and professor, Department of Pharmaceutics, Dhanalakshmi Srinivasan college of Pharmacy, Perambalur, Tamil Nadu, India. 3 4 5 6 7 Students, Dhanalakshmi Srinivasan college of Pharmacy, Perambalur, Tamil Nadu, India.
Published Online: September-October 2026
Pages: 113-119
Cite this article
No DOIReferences
1. Junaid R Shaikh and MK Patil. Qualitative tests for preliminary phytochemical screening: An overview. International Journal of Chemical Studies. 2020;8(2):603-608, DOI: https://doi.org/10.22271/chemi.2020.v8.i2i.8834.
2. Vaishnavi V. Gaikwad, Sameeksha R. Gitaje, Saurabh D. Joshi, Shrirang V. Kharmate, Dipak R. Phalle, Mrudula P. More, Mrunal A. Mali and Pratibha P. Shingade. Mechanisms of Inflammation Associated with Chronic Diseases: A Brief Review. Journal of Advances in Medicine and Medical Research. 2025; 37(3): 48-56.
3. Krishna Reddy IK, Yerragopu AK and Chamarthi SK. A Review on Plants having Anti Inflammatory Activity. Open Access Journal of Pharmaceutical Research. 2020;4(4), DOI: 10.23880/oajpr-16000217.
4. A. Gowtham Sashtha, S. Mohamed Halith, M. Janani, S. Janani, T. Javith Ahamed, J. Jayaraman, G. Jayasri. In-vitro Screening of Antioxidant and Anti-inflammatory Activities of Vigna Stipulacea Methanolic Leaf Extract: A Review. Journal of Advance and Future Research(www.jaafr.org). 2026; 4(6).
5. D. Saranya and J. Sekar. GC-MS and FT-IR Analyses of Ethyl acetate Leaf extract of Abutilon indicum (L.) Sweet. International Journal of Advanced Research in Biological Sciences. 2016; 3(2); 193-197.
6. Kuntal Das, M. Saifullakhan, N. Namratha, R. Swetha and Sevgi Gezici. Comparative phytochemical screening, elemental content and chromatographic evaluation for detection and quantification of polyphenolic compounds for strong antioxidant activity of various extracts of Abutilon indicum (Link) Sweet leaves. Annals of Phytomedicine. 2019;8(1): 36-44. DOI: 10.21276/ap.2019.8.1.4.
7. Ranjana Singh and Vijay D. Mendhulkar. FTIR studies and spectrophotometric analysis of natural antioxidants, polyphenols and flavonoids in Abutilon indicum (Linn) Sweet leaf extract. Journal of Chemical and Pharmaceutical Research. 2015; 7(6):205-211.
8. N. Prabha, P. Parthiban, P. Arjun and J. Bhuvana. Bioactive Compounds Identification in Abutilon indicum Through GC-MS Analysis AND Molecular Docking Study. http://www.rasayanjournal.com. 2025;18(1):641-647.
9. N R Jadhav, R B Patil. Analysing the Phytochemistry and Bioactive Compounds of Abutilon indicum for antidiabetic activity Using TLC, HPTLC, GC-MS in Aqueous, Ethanol, and Chloroform Solvents for Pharmacognosy Determinations. Journal of Pharmaceutical Research. 2024;23(1):40-48.
10. Archna Sharma, R.A. Sharma, and Hemlata Singh. Phytochemical and Pharmacological Profile of Abutilon Indicum L Sweet: A Review. International Journal of Pharmaceutical Sciences Review and Research. 2013;20(1): 120-127.
11. Ramadoss Karthikeyan, PannemVenkatesh, Nesepogu Chandrasekhar. Morpho anatomical studies of leaves of Abutilon indicum (linn.) sweet. Asian Pacific Journal of Tropical Biomedicine. 2012.
12. S Rajeshwari and SP Sevarkodiyone. Medicinal properties of Abutilon Indicum. Open J Plant Sci. 2018; 3(1): 22–25. DOI: 10.17352/ojps.000011.
13. Vasanthan G, Tamilarasan M, Chandran N, Monisha J, Sirumalar S, Suvitha S, Thamaraikavi K. The Healing Giant: Exploring The Multifaceted Uses of Abutilon indicum. World Journal of Pharmaceutical Research. 2025;14(2): 356-375.
14. R. Nithyatharani, U.S. Kavitha. Abutilon Indicum– An Excellent Phytomedicine: A Review. International Journal of Creative Research Thoughts. 2018;6(1).
15. Arora S, Singh DP, Saini A, Kumar A. Pharmacognostic investigation on roots & leaves extract of Abutilon indicum Linn. International Journal of Research and Development in Pharmacy and Life Sciences. 2013 Aug–Sept; 2(5): 567–573.
16. P. Pavithra, S Kavimani, P Pavazhaviji, A Hemalatha, R Snega. A review on phytochemical screening and pharmacological activities of fruit of Indian mallow. Indian Journal of Pharmacy and Pharmacology. 2023;10(4):265–271.
17. Krishnaiah, D., Devi, T., Bono, A., & Sarbatly, R. Studies on phytochemical constituents of six Malaysian medicinal plants. Journal of Medicinal Plants Research. (2009);3(2), 67-72.18. Zhang, A., Sun, H., & Wang, X. Recent advances in metabolomics in plant research. Molecular Plant. 2014; 7(4), 521-535.
19. Justesen, U., Knuthsen, P., & Leth, T. Quantitative analysis of flavanols, flavones, and flavanones in fruits, vegetables and beverages by high-performance liquid chromatography with photo-diode array and mass spectrometric detection. Journal of Chromatography A.1988; 799, 101–110.
20. Cuyckens, F., & Claeys, M. Mass spectrometry in flavonoid analysis. Journal of Mass Spectrometry. (2004);39, 1-15.
21. Robbins, R. J. Phenolic acids in foods: An overview of analytical methodology. Journal of Agricultural and Food Chemistry. 2003; 51, 2866-2887.
22. Stobiecki, M. Application of mass spectrometry for identification of flavonoids. Phytochemistry. 2000; 54, 237–256.
23. Lin, L.Z., et al. A screening method for the identification of glycosylated flavonoids and other phenolic compounds. Journal of Agricultural and Food Chemistry. (2016); 64(5), 1046–1070.
24. Psychogios, N., et al. The human serum metabolome. PLoS ONE. (2011); 6(2), e16957.
25. Wishart, D.S., et al. HMDB 4.0: Human Metabolome Database. Nucleic Acids Research. (2018); 46, D608–D617.
26. Clifford, M.N., et al. LC-MS analysis of chlorogenic acids. Journal of Agricultural and Food Chemistry. (2003); 51, 2900–2911.
27. Han, X., & Gross, R.W. Shotgun lipidomics analysis. Mass Spectrometry Reviews. (2005); 24, 367–412.
28. Chandra, S., Chatterjee, P., Dey, P., & Bhattacharya, S. Evaluation of in vitro anti-inflammatory activity of coffee against the denaturation of protein. Asian Pacific Journal of Tropical Biomedicine. (2012); 2(1), 178-180. https://doi.org/10.1016/S2221-1691(12)60154-3.
2. Vaishnavi V. Gaikwad, Sameeksha R. Gitaje, Saurabh D. Joshi, Shrirang V. Kharmate, Dipak R. Phalle, Mrudula P. More, Mrunal A. Mali and Pratibha P. Shingade. Mechanisms of Inflammation Associated with Chronic Diseases: A Brief Review. Journal of Advances in Medicine and Medical Research. 2025; 37(3): 48-56.
3. Krishna Reddy IK, Yerragopu AK and Chamarthi SK. A Review on Plants having Anti Inflammatory Activity. Open Access Journal of Pharmaceutical Research. 2020;4(4), DOI: 10.23880/oajpr-16000217.
4. A. Gowtham Sashtha, S. Mohamed Halith, M. Janani, S. Janani, T. Javith Ahamed, J. Jayaraman, G. Jayasri. In-vitro Screening of Antioxidant and Anti-inflammatory Activities of Vigna Stipulacea Methanolic Leaf Extract: A Review. Journal of Advance and Future Research(www.jaafr.org). 2026; 4(6).
5. D. Saranya and J. Sekar. GC-MS and FT-IR Analyses of Ethyl acetate Leaf extract of Abutilon indicum (L.) Sweet. International Journal of Advanced Research in Biological Sciences. 2016; 3(2); 193-197.
6. Kuntal Das, M. Saifullakhan, N. Namratha, R. Swetha and Sevgi Gezici. Comparative phytochemical screening, elemental content and chromatographic evaluation for detection and quantification of polyphenolic compounds for strong antioxidant activity of various extracts of Abutilon indicum (Link) Sweet leaves. Annals of Phytomedicine. 2019;8(1): 36-44. DOI: 10.21276/ap.2019.8.1.4.
7. Ranjana Singh and Vijay D. Mendhulkar. FTIR studies and spectrophotometric analysis of natural antioxidants, polyphenols and flavonoids in Abutilon indicum (Linn) Sweet leaf extract. Journal of Chemical and Pharmaceutical Research. 2015; 7(6):205-211.
8. N. Prabha, P. Parthiban, P. Arjun and J. Bhuvana. Bioactive Compounds Identification in Abutilon indicum Through GC-MS Analysis AND Molecular Docking Study. http://www.rasayanjournal.com. 2025;18(1):641-647.
9. N R Jadhav, R B Patil. Analysing the Phytochemistry and Bioactive Compounds of Abutilon indicum for antidiabetic activity Using TLC, HPTLC, GC-MS in Aqueous, Ethanol, and Chloroform Solvents for Pharmacognosy Determinations. Journal of Pharmaceutical Research. 2024;23(1):40-48.
10. Archna Sharma, R.A. Sharma, and Hemlata Singh. Phytochemical and Pharmacological Profile of Abutilon Indicum L Sweet: A Review. International Journal of Pharmaceutical Sciences Review and Research. 2013;20(1): 120-127.
11. Ramadoss Karthikeyan, PannemVenkatesh, Nesepogu Chandrasekhar. Morpho anatomical studies of leaves of Abutilon indicum (linn.) sweet. Asian Pacific Journal of Tropical Biomedicine. 2012.
12. S Rajeshwari and SP Sevarkodiyone. Medicinal properties of Abutilon Indicum. Open J Plant Sci. 2018; 3(1): 22–25. DOI: 10.17352/ojps.000011.
13. Vasanthan G, Tamilarasan M, Chandran N, Monisha J, Sirumalar S, Suvitha S, Thamaraikavi K. The Healing Giant: Exploring The Multifaceted Uses of Abutilon indicum. World Journal of Pharmaceutical Research. 2025;14(2): 356-375.
14. R. Nithyatharani, U.S. Kavitha. Abutilon Indicum– An Excellent Phytomedicine: A Review. International Journal of Creative Research Thoughts. 2018;6(1).
15. Arora S, Singh DP, Saini A, Kumar A. Pharmacognostic investigation on roots & leaves extract of Abutilon indicum Linn. International Journal of Research and Development in Pharmacy and Life Sciences. 2013 Aug–Sept; 2(5): 567–573.
16. P. Pavithra, S Kavimani, P Pavazhaviji, A Hemalatha, R Snega. A review on phytochemical screening and pharmacological activities of fruit of Indian mallow. Indian Journal of Pharmacy and Pharmacology. 2023;10(4):265–271.
17. Krishnaiah, D., Devi, T., Bono, A., & Sarbatly, R. Studies on phytochemical constituents of six Malaysian medicinal plants. Journal of Medicinal Plants Research. (2009);3(2), 67-72.18. Zhang, A., Sun, H., & Wang, X. Recent advances in metabolomics in plant research. Molecular Plant. 2014; 7(4), 521-535.
19. Justesen, U., Knuthsen, P., & Leth, T. Quantitative analysis of flavanols, flavones, and flavanones in fruits, vegetables and beverages by high-performance liquid chromatography with photo-diode array and mass spectrometric detection. Journal of Chromatography A.1988; 799, 101–110.
20. Cuyckens, F., & Claeys, M. Mass spectrometry in flavonoid analysis. Journal of Mass Spectrometry. (2004);39, 1-15.
21. Robbins, R. J. Phenolic acids in foods: An overview of analytical methodology. Journal of Agricultural and Food Chemistry. 2003; 51, 2866-2887.
22. Stobiecki, M. Application of mass spectrometry for identification of flavonoids. Phytochemistry. 2000; 54, 237–256.
23. Lin, L.Z., et al. A screening method for the identification of glycosylated flavonoids and other phenolic compounds. Journal of Agricultural and Food Chemistry. (2016); 64(5), 1046–1070.
24. Psychogios, N., et al. The human serum metabolome. PLoS ONE. (2011); 6(2), e16957.
25. Wishart, D.S., et al. HMDB 4.0: Human Metabolome Database. Nucleic Acids Research. (2018); 46, D608–D617.
26. Clifford, M.N., et al. LC-MS analysis of chlorogenic acids. Journal of Agricultural and Food Chemistry. (2003); 51, 2900–2911.
27. Han, X., & Gross, R.W. Shotgun lipidomics analysis. Mass Spectrometry Reviews. (2005); 24, 367–412.
28. Chandra, S., Chatterjee, P., Dey, P., & Bhattacharya, S. Evaluation of in vitro anti-inflammatory activity of coffee against the denaturation of protein. Asian Pacific Journal of Tropical Biomedicine. (2012); 2(1), 178-180. https://doi.org/10.1016/S2221-1691(12)60154-3.
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