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- Vol. 6 Issue 2
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Microbiota Transplantation in Oral Diseases and Systemic Diseases with Oral Manifestations
Authors
1 2 Interns, RVS Dental College and Hospital, Coimbatore, Tamilnadu, India. 3 4 Interns, RVS Dental College and Hospital, Coimbatore, Tamilnadu, India. 5 6 Interns, RVS Dental College and Hospital, Coimbatore, Tamilnadu, India. 7 Interns, RVS Dental College and Hospital, Coimbatore, Tamilnadu, India. 8 Professor, Department of Oral Pathology and Microbiology, RVS Dental College and Hospital, Coimbatore, Tamil Nadu, India. 9 Professor and Head, Department of Oral Pathology and Microbiology, RVS Dental College and Hospital, Coimbatore, Tamil Nadu, India.
Article Information
- Published In
- Volume 6, Issue 2 (2026)
- Published Online
- March-April 2026
- Pages
- 246-249
- Article Type
- Review Article
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Abstract
View PDFMicrobiota transplantation has emerged as a novel therapeutic strategy aimed at restoring microbial balance in dysbiotic environments. While fecal microbiota transplantation (FMT) has demonstrated clinical success in gastrointestinal disorders, its conceptual extension to the oral cavity—termed oral microbiota transplantation (OMT)—is gaining increasing attention. Oral diseases such as dental caries, periodontitis, and halitosis are closely associated with microbial dysbiosis, and similar imbalances are implicated in systemic diseases with oral manifestations, including diabetes mellitus, cardiovascular diseases, gastrointestinal disorders, rheumatoid arthritis, and cancer. This review explores the biological basis, mechanisms, clinical applications, and challenges of microbiota transplantation in oral and systemic conditions, highlighting current evidence and future directions.
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