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Review Article

An Overview on Zoonotic Diseases

M. K. Vijaya Lakshmi1*1 Puniparthi Sunitha2 K. Pooja,3 C. Sudharshan4 P. Varshini5 G. Ramya, S. Hemnath6
1*Associate Professor, Faculty of Pharmacy, Bharath Institute of Higher Education and Research, Selaiyur, Chennai, Tamilnadu, India. 234567 B. Pharm Students, Bharath Institute of Higher Education and Research, Selaiyur, Chennai, Tamilnadu, India.

Published Online: May-June 2025

Pages: 35-40

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Abstract

Zoonotic diseases, or zoonoses, are infections transmitted from animals to humans, caused by pathogens such as bacteria, viruses, parasites, or fungi. These diseases can spread through direct contact with animals, consumption of contaminated food or water, or via vectors like mosquitoes and ticks. Understanding zoonotic diseases is crucial due to their significant impact on public health, economies, and food security. Notably, over 60% of emerging infectious diseases in humans are zoonotic, with factors like globalization, increased human-animal interactions, and climate change contributing to their rapid spread. The COVID-19 pandemic, suspected to have originated from an animal source, underscores the potential of zoonotic diseases to cause global health crises. Economically, outbreaks can disrupt agriculture and trade, leading to substantial losses, as seen with avian influenza and foot-and-mouth disease. Food safety is also compromised through diseases like salmonellosis, transmitted via contaminated animal products. Environmental impacts include biodiversity loss due to wildlife diseases, exacerbated by habitat destruction and deforestation. The One Health approach, integrating human, animal, and environmental health, is essential for effective management of zoonotic diseases. Zoonoses can be categorized based on causative agents: bacterial (e.g., anthrax, leptospirosis), viral (e.g., rabies, Ebola), parasitic (e.g., toxoplasmosis), and fungal (e.g., ringworm). Transmission routes include direct contact, indirect contact, vector-borne, foodborne, airborne, and waterborne pathways. Common zoonotic diseases encompass rabies, influenza, tuberculosis, and Ebola, each posing unique challenges to global health. Addressing zoonotic diseases requires comprehensive strategies, including surveillance, research, and cross-sector collaboration, to mitigate their impact on human and animal populations worldwide.

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